# Q1: A Bronsted acid becomes __________ upon losing a proton.

A highly reactive
B its conjugate acid
C its conjugate base
D a hydronium ion

ANS:C - its conjugate base

# Q2: A compound that is capable of forming hydrogen bonds with water

A is probably held together by noncovalent bonds
B contains at least some polar covalent bonds
C should act as a good buffer for acids and bases
D does not dissolve well in water

ANS:B - contains at least some polar covalent bonds

# Q3: The dissociation constant of H2O at 25° C is

A 10-14 M
B 1014 M
C 10-7 M
D 107 M

ANS:A - 10-14 M

The dissociation constant is the degree of dissociation of the ions of a molecule. In this case: H+ and OH-.

The Pure water is completely ionized. therefore, has a neutral pH. pH = -log[H+]
7 = -log [H+] therefore, [H+] = 10^-7M.

# Q4: Which of the following indicates that the pK of an acid is numerically equal to the pH of the solution when the molar concentration of the acid and its conjugate base are equal?

A Michaelis-Menten equation
B Haldanes equation
C Henderson-Hasselbalch equation
D Hardy-Windberg law

ANS:C - Henderson-Hasselbalch equation

# Q5: Which of the following acid/base pairs act as natural buffers in living systems?

A H2CO3/HCO3-
B H2PO4-/HPO42-
C Histidine+/histidine
D All of these

ANS:D - All of these

# Q6: If protein is made exclusively from nonpolar amino acids, then it will this protein interact with water?

A be repelled by water
B It will be attracted to water
C It will form a membrane in water
D It will act as a buffer and stabilize the pH

ANS:A - be repelled by water

# Q7: Weak acids generally have pKa

A values less than 1
B pKa values greater than 2
C been seldom found in living systems
D that cannot be used to buffer

ANS:B - pKa values greater than 2

# Q8: Which of the following character does not apply to water?

A The water molecule is asymmetric
B The water molecule readily forms hydrophobic interactions
C The covalent bonds in water are highly polarized
D All three atoms in the water molecule readily form hydrogen bonds

ANS:B - The water molecule readily forms hydrophobic interactions

Non-polar solute dissolve partially in Water thus, water form a cage around the solute this structure is called clathrate.

# Q9: Salt dissolves well in water as water molecules

A form hydrogen bonds with the positively and negatively charged ions
B make nonpolar covalent bonds with the positively charged ions only
C surround the ions because of their charge but do not form hydrogen bonds
D share electrons with the ions to make polar covalent bonds

ANS:C - surround the ions because of their charge but do not form hydrogen bonds

# Q10: The reactions of molecules

A are the reactions of the functional groups
B are independent of the functional groups
C require an enzyme in all cases
D all of the above

ANS:A - are the reactions of the functional groups

# Q11: The reason that fats contain more energy than simple sugars, is fats have many more

A carbon atoms
B hydrogen atoms
C covalent bonds
D hydrogen bonds

ANS:C - covalent bonds

# Q12: Buffer solutions

A will always have a pH of 7
B are rarely found in living systems
C cause a decrease in pH when acids are added to them.
D tend to maintain a relatively constant pH.

ANS:D - tend to maintain a relatively constant pH.

# Q13: The main difference between an acid and a base is that

A bases are polar molecules and acids are not
B acids are polar molecules and bases are not
C bases donate hydrogen ions in water while acids accept hydrogen ions
D acids donate hydrogen ions in water while bases accept hydrogen ions

ANS:D - acids donate hydrogen ions in water while bases accept hydrogen ions

# Q14: The pH of a solution is determined by

A concentration of salt
B relative concentration of acids and bases
C dielectric constant of the medium
D environmental effect

ANS:B - relative concentration of acids and bases

# Q15: Which of the following will easily dissolve in a polar solvent?

A gasoline (heptanes & octanes)
B methane
C argon
D sodium chloride

ANS:D - sodium chloride

Polar solvents only discovered polar and ionic compounds, Al hydrocarbons (eg methane, Vaseline) are non-polar and only dissolved on polar and no ionic compounds.

# Q16: Which of the following statements about water is correct?

A It is critical for many of the chemical processes found in living systems
B Polar substances that can form hydrogen bonds will dissolve in it
C Nonpolar substances like oils are not soluble in it
D All of the above

ANS:D - All of the above

Because water is neutral.

# Q17: The strength of an acid depends on

A number of neutrons gain
B electronegativity
C number of double bonds
D number of protons released

ANS:B - electronegativity

# Q18: Which of the following organic groups are found in naturally occuring amino acids?

A Guanidinium ion
B Indole
C Imidazole
D All of these

ANS:D - All of these

# Q19: Polyprotic acids such as H3PO4, can act as acid-base buffers

A only in combination with polyprotic bases
B if their concentration is kept low
C at pH values around neutrality
D at pH values around any of their pKa's

ANS:D - at pH values around any of their pKa's

# Q20: Most of the important functional groups in biological molecules contain

A oxygen and/or nitrogen and are acidic
B oxygen and a phosphate
C nitrogen and a phosphate
D oxygen and/or nitrogen and are polar

ANS:D - oxygen and/or nitrogen and are polar

# Q21: Which of the following statements about covalently bonded molecules is false?

A Electrons are shared between the atoms that make up the molecule
B Noncovalent bonds may also be present, especially if the molecule is large
C Such molecules often result from the interaction of ionized atoms
D The chemical bonds that hold the molecule together are relatively strong

ANS:C - Such molecules often result from the interaction of ionized atoms

A noncovalent
B covalent
C ionic
D hydrogen

ANS:B - covalent

# Q23: A solution with pH = 5 is __________ than a solution with pH = 7.

A 2 times more basic
B 10 times more basic
C 10 times more acidic
D 100 times more acidic

ANS:D - 100 times more acidic

# Q24: Hydrogen bonds and hydrophilic interactions are types of

A weak chemical bonds that hold together the atoms within a molecule
B strong chemical bonds that hold together the atoms within a molecule
C weak chemical bonds that link together separate molecules
D strong chemical bonds that link together separate molecules

ANS:C - weak chemical bonds that link together separate molecules

# Q25: Who discovered and described the blood groups (ABO) classification?

A Theodor Kocher
B Karl Landsteiner
C Otto Warburg
D Karl Hooper

ANS:B - Karl Landsteiner

# Q26: The elements oxygen, nitrogen, and carbon

A can all form covalent bonds with other elements
B contain protons and neutrons in their atomic nuclei
C are common elements in the molecules that make up living organisms
D All of the above

ANS:D - All of the above

How oxygen and nitrogen and carbon form covelent bond with other molecular?

# Q27: The lone pair electrons on oxygen in a H20 molecule

A carry a partial positive charge
B are not important for the properties of water
C carry a partial negative charge
D form covalent bonds in ice

ANS:C - carry a partial negative charge

A methanol
B ethanol
C butanol
D octanol

ANS:A - methanol

A 7
B 7 x 10-7
C 5 x 10-7
D 1 x 10-7

ANS:D - 1 x 10-7

A DNA
B Strong base
C Phospholipid
D Protein

ANS:D - Protein

# Q31: The effectiveness or capacity of a buffer solution can be affected by

A molar concentration of the buffer components
B concentration of the conjugate base to the weak acid
C both (a) and (b)
D temperature of buffer components

ANS:C - both (a) and (b)

# Q32: H2O and CH4 are both examples of

A molecules
B ions
C acids
D none of these

ANS:A - molecules