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DNA Sequencing, Mutation and Repair - Medical Science

Q1:

A nonsense mutation may result into

A an abnormal elongation of a polypeptide

B a large deletion within the reading frame of a gene

C a premature termination of the synthesis of a polypeptide

D modification of mRNA

ANS:C - a premature termination of the synthesis of a polypeptide

As described in answer of 2nd que, nonsense mutation results in to formation of the nonsense codon in the transcript. So when a transcript (m-RNA) goes to get translated, it terminates at the nonsense codon that is resulted during nonsense mutation.