

Amino Acid Metabolism - Medical Science
Q1: Histidine is degraded to α-ketoglutarate and is described as aA gluco amino acid
B glucogenic amino acid
C ketogenic amino acid
D keto-gluco amino acid
ANS:B - glucogenic amino acid Histidine is deaminated to urocanic acid, which is converted to 4-imidazolone 5-propionate. Hydrolysis of the later gives N-formiminoglutamate (FIGlu, which donates its formimino group to tetrahydrofolate, leaving glutamate which is then converted to alpha-ketoglutarate. Alpha-ketoglutarate is an intermediate in the Kreb's Cycle. Any amino acid whose catabolism gives pyruvate or one of the intermediate of Citric Acid Cycle is glycogenic amino acid. |


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