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Transcription and Regulation - Medical Science

Q1:

In prokaryotes, transcription is

A terminated by the stop codon

B terminated by a protein called rho

C terminated by a poly A sequence

D terminated by a start codon

ANS:B - terminated by a protein called rho

Option B is correct.

In prokaryotes, termination occurs by two ways:

a. Intrinsic mechanism- here, RNA polymerase is destabilized hence, the chain is terminated.
b. Rho-dependent mechanism- Rho protein, basically, a helicase unwinds DNA-RNA hybrid, thus chain is terminated.