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Transcription and Regulation - Medical Science

Q1:

RNA polymerase holoenzyme initiates transcription which involves

A recognition of the -10 sequence and -35 sequence

B recognition of the -10 sequence only

C recognition of the -35 sequence only

D none of the above

ANS:A - recognition of the -10 sequence and -35 sequence

Both are consensus sequences.

-10 sequence (TATAAT) is also called the Pribnow box.