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Cell Signalling and Transduction

Q1:

Self-phosphorylation is an excellent mechanism for triggering specific catalytic function of the proteins involved in signal cascades because it

A changes the shape and thus the enzymatic activity of the proteins involved

B makes the receptor more likely to capture the signaling, molecule

C allows hydrophilic signaling molecules to cross the plasma membrane

D None of the above

ANS:A - changes the shape and thus the enzymatic activity of the proteins involved

Best example is RTK receptor which by autophosphorylation create site for docking which lead signal proceed.



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