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Protein Stability

Q1: Since ΔG° = -RTlnK

A a 10-fold increase in K decreases ΔG° by about 10-fold

B a 10-fold decrease in K decreases ΔG° by about 2.3*RT

C a 10-fold increase in K decreases ΔG° by about 2.3*RT

D a 10-fold decrease in K increases ΔG° by about 10-fold

ANS:C - a 10-fold increase in K decreases ΔG° by about 2.3*RT

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