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Enzymes - Medical Science

Q1:

The cleavage specificity of trypsin and chymotrypsin depend in part on the

A proximity of Ser 195 to the active site or specificity pocket

B size, shape, and charge of the active site or specificity pocket

C presence of a low-barrier hydrogen bond in the active site or specificity pocket

D absence of water in the active site

ANS:A - proximity of Ser 195 to the active site or specificity pocket

The answer is correct becouse specificity of enzyme primerly depend on size, shape and charge of acrive site.