Transcription and Regulation - Medical Science

Q1:

The major function of RNA polymerase's sigma factor is

A recognition of the translational stop sequence

B recognition of the transcriptional start sequence

C recognition of the transcriptional stop sequence

D recognition of the translational start sequence

ANS:B - recognition of the transcriptional start sequence

Sigma factor protein is a sub unit of RNA polymerase.

It's role is to recognize the promoter sequence on a DNA (gene) and binding of RNA polymerase to promoter region.