Enzymes

Q1: The role of Asp 102 and His 57 during trypsin catalysis is to

A clamp the substrate into the active site

B keep the specificity pocket open

C neutralize the charge on the other's side chain

D function as a proton shuttle

ANS:C - function as a proton shuttle

Asp 102 and His 57, how do they function as proton shuttles?



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