Structure and Properties of Peptides - Medical Science

Q1:

The same peptide, Val-Lys-Glu-Met-Ser-Trp-Arg-Ala. was digested with chymotrypsin to produce

A Val-Lys + Glu-Met-Ser + Trp-Arg-Ala.

B Val-Lys-Glu-Met-Ser-Trp + Arg-Ala.

C Val-Lys-Glu-Met-Ser + Trp-Arg-Ala.

D Val-Lys-Glu-Met + Ser-Trp-Arg-Ala.

ANS:B - Val-Lys-Glu-Met-Ser-Trp + Arg-Ala.

Chymotrypsin generally cleaves at carboxyl side of aromatic amino acids residues (Tryptophan, Tyrosine & Phenylalanine) and proline residue's must absent just after aromatic amino acids residues.