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Microorganisms and Disease

Q1: Type III secretion systems are used to inject "effector" proteins directly into a host cell. Salmonella uses a type III secretion system to help the pathogen to

A survive the acid pH of the stomach

B secrete LT (heat labile toxin) and ST (heat stable toxin) into the lumen of the intestine

C survive within macrophages

D activate T cells to proliferate and secrete cytokines

ANS:C - survive within macrophages

Most of the gram negative bacteria having the needle like structure on surface which directly inject and secrete the effector proteins into host cell. The secreted proteins helps the pathogen survival and to escape from immune response.



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