Antigen Antibody Reaction - Medical Science

Q1:

Weil-Felix reaction is based on sharing of antigens between

A sheep RBCs and EB virus

B mycoplasma and human O group RBCs

C rickettsial antigens and antigens of certain strains of Proteus

D none of these

ANS:C - rickettsial antigens and antigens of certain strains of Proteus

Weil-Felix is a nonspecific agglutination test which detects anti-rickettsial antibodies in patient's serum. Weil-Felix test is based on cross-reactions which occur between antibodies produced in acute rickettsial infections with antigens of OX (OX 19, OX 2, and OXK) strains of Proteus species.