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Structure and Properties of Amino Acids - Medical Science

Q1:

Which amino acids would most likely reside in the membrane-anchoring domain of a membrane embedded protein?

A Isoleucine, valine and phenylalanine

B Phenylalanine, valine, and aspartate

C Leucine, threonine, and lysine

D Lysine, arginine and histidine

ANS:A - Isoleucine, valine and phenylalanine

Membrane-embedded proteins must be hydrophobic. So we need to choose which option of amino acids have hydrophobic are chains.

And charged are groups would disrupt membrane stability. We need to choose unchanged amino acids.