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Enzymes

Q1: Which of the following is false statement with regard to comparison between Serine and HIV proteases?

A Both use nucleophilic attack to hydrolyze the peptide bond

B Both require water to complete the catalytic cycle

C Both forms an acyl-enzyme intermediate

D Both show specificity for certain amino acid sequences

ANS:C - Both forms an acyl-enzyme intermediate

Because serine form tetrahedral intermediate and acyl-enzyme intermediate while HIV form just acyl-enzyme intermediate.



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