Q1: Which of the following is false statement with regard to comparison between Serine and HIV proteases?

A Both require water to complete the catalytic cycle

B Both show specificity for certain amino acid sequences

C Both use nucleophilic attack to hydrolyze the peptide bond

D Both forms an acyl-enzyme intermediate

ANS:C - Both forms an acyl-enzyme intermediate

Because serine form tetrahedral intermediate and acyl-enzyme intermediate while HIV form just acyl-enzyme intermediate.

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