

Genetic Code and Regulation - Medical Science
Q1: Which of the following techniques was carried out by Nirenberg and Matthaei in 1961 to determine the first codon?A In vitro synthesis of a polypeptide using UUUUU
B Labeled peptide binding to a ribosome
C Mixed co-polymer mRNA synthesis
D none of the above
ANS:A - In vitro synthesis of a polypeptide using UUUUU This was the easiest methods to find which codon codes for which Amino acid. If a sequence is generated such that it contains all Uracils or Thymines, e.g UUUU, irrespective of what the reading frame only 1 type of Amino acid will be coded and polymerised. |


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