

DNA Structure and Replication - Medical Science
Q1: DNA gyrase in E. coliA adds positive supercoils to chromosomal DNA
B can be inhibited with antibiotics
C is required only at the oriC site
D performs the same function as helicase in eukaryotes
ANS:B - can be inhibited with antibiotics DNA gyrase in E.coli relaxes the tension in the strand that builds ahead of the replication fork during replication. If this fails to occur, replication will cease and the cell will die. This is employed by anti biotics to inhibit replication of bacteria such as E.Coli. |


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