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Enzymes and Kinetics

Q1: Given an enzyme with a Km = 10m M and Vmax = 100 m mol/min. If [S] = 100 m M, which of the following will be true?

A A 10 fold increase in Vmax would increase velocity 10 fold y

B A 10 fold decrease in Km would increase velocity

C Both (a) and (b)

D A 10 fold increase in Vmax would decrease velocity 20 fold

ANS:A - A 10 fold increase in Vmax would increase velocity 10 fold y

10 fold decrease in km means the km'=10 km (bcoz affinity = 1/km not only km), so we will increase so the second statement is false and the answer should be the option (A).



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