Which institution's researchers made a significant breakthrough in the mass production of recombinant proteins by utilizing Monosodium Glutamate (MSG)?

ANS:B - IISc Bengaluru

Researchers from the Indian Institute of Technology (IIT) Madras made a significant breakthrough in the mass production of recombinant proteins by utilizing Monosodium Glutamate (MSG). This innovative approach leverages MSG, commonly used as a flavor enhancer in the food industry, to enhance the efficiency of protein expression in microbial systems. By incorporating MSG into the growth medium, the researchers were able to improve the yield and quality of recombinant proteins produced through bacterial fermentation processes. This method offers a cost-effective and scalable solution for producing high quantities of recombinant proteins, which are crucial for various applications, including pharmaceuticals, industrial enzymes, and research. The use of MSG not only optimizes the growth conditions for microorganisms but also helps in achieving better control over the protein production process. This breakthrough has the potential to transform the biotechnology industry by providing a more efficient and economical means of producing valuable proteins, thereby accelerating research and development in fields such as drug discovery, diagnostics, and therapeutic protein production. The work of IIT Madras researchers highlights the intersection of food science and biotechnology, showcasing how commonly used substances can be repurposed to address challenges in protein manufacturing.